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Sigfried TONGGE
2. Pharmacopoeia Indonesianedisi IV
4. R. Textbook Voight Pharmaceutical Technology
At this time, the development of science and technology is growing very rapidly buffet trays once. Almost all areas of the industry are also taking part in this development, ranging from the food industry, beverage, and also in the world pharmaceutical industry. In the pharmaceutical and food industry buffet trays began to grow rapidly and varied. Therefore, this process takes on a quality control of the raw materials to be used in the industry, this is done because a lot of counterfeiting going on these raw materials are likely buffet trays to be harmful to consumers. So it takes a ketelitiaan in analyzing the purity of the raw materials.
For these reasons, specific gravity lab is done, so that we as a practitioner can prevent the use of raw materials such fake. P raktikum specific gravity buffet trays is a very simple buffet trays practice that can be done in determining the purity of a substance either solid or liquid substance.
Method of determining the specific gravity is very important to know, because knowing the weight of the type we can determine the purity of a preparation either solution buffet trays or solid form. Besides, in the pharmaceutical world learn the specific gravity buffet trays is needed buffet trays to facilitate pharmacists in particular at the time of formulating the drug dosage. Because by knowing its specific gravity then we can determine buffet trays whether the materials we use raw materials that it is genuine or artificial raw materials, so that later made drugs are safe for consumption by patients
Specific gravity of a substance is defined as the ratio of the weight of a substance to an equal volume of water weighed in air at the same temperature (Indonesian Pharmacopoeia III edition buffet trays case 767). Unless otherwise stated in the individual monograph, the determination of specific gravity used only for liquids, based on the ratio of the weight of the substance in air at a temperature of 25 0 to the weight of the water with the same volume and temperature. When the temperature specified in the monograph, the specific gravity is the ratio of the weight of a substance in the air at the temperature set on the volume and weight of water with the same temperature. When the temperature is 25 0 C solid substance, assign buffet trays specific buffet trays gravity at the temperature indicated on each monograph, and refers to the water that stays at 25 0 C (case IV Indonesian Pharmacopoeia 1030 Edition).
Specific gravity of a substance is the result obtained by dividing the weight of the substance with water weight, in Pycnometer. Unless otherwise stated in the development of monograph, buffet trays both set at a temperature of 25 º (Indonesian Pharmacopoeia 1030 Edition IV thing).
Weight per ml of liquid determined by dividing the weight of the liquid buffet trays in the air expressed in g, of the amount of fluid that fills Pycnometer buffet trays at a predetermined temperature with Pycnometer capacity expressed in ml, at the same temperature (Indonesian Pharmacopoeia 1030 Edition IV thing).
According to the specific gravity of the water table FI IV, 1030
Pycnometer is a tool used to measure the value of the density or the density of the fluid. Pycnometer is a tool for measuring the specific gravity of a liquid and a solid volume with a capacity of between 10 ml - 25 ml, the lid has a small channel shaped hole that functioned to remove excess substances too much, and also to determine whether the full content of the test substance in in Pycnometer.
Density of a substance can be calculated directly measure the weight of the substance buffet trays in Pycnometer (by weighing) and volume substances (determined buffet trays by Pycnometer). The principle of this method is based on the determination of the mass of the liquid and the determination of the fluid occupied preference. Pycnometer space is done by weighing the water. Pycnometer method accuracy will increase until a certain optimum Pycnometer with increasing volume. Optimum is located approximately 30 ml fill space. There are two types Pycnometer, namely the type of bottle with dropper type.
Aerometer is a tool used to measure the density of liquids. This device consists buffet trays of a tube whose bottom scale given the burden of mercury, that can float in the liquid to be measured specific gravity.
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